Insulin resistance is the main channel.
How many specialties does it feed?

The book

Against the Current

A pharmacist's guide to reversing what medicine calls permanent. Every condition on this map shows up in the book, with the references printed in the back.

Kyle Rootsaert, PharmD, BC-ADM

Get the book

Paperback, Kindle and audiobook

Every link here is an association, not proof. Each one carries its sources and the case against it.

Pick a condition

Check your own numbers

Are you at risk, or do you already have metabolic syndrome?

Metabolic syndrome is a published checklist of five. Three or more qualifies. Enter your numbers and count them. No score. No diagnosis.

The published criteria set waist and HDL differently for men and women. Everything else is the same number.

Tape measure, just above your hip bonesCounts at 35 inches or more
On your lipid panelCounts at 150 mg/dL or more
On your lipid panelCounts below 50 mg/dL
Any cuff, home or pharmacyCounts at 130 over 85 or more, either number
/
Glucose on your metabolic panelCounts at 100 mg/dL or more

Enter a number to start.

What to do about itThe book walks through each of the five, and what moves them.

The Unscripted Lab: the free 14-day CGM lab that goes with the book.Want to watch your own numbers move? Use a glucose sensor or a ketone meter.Read the Lab safety rules first if you have type 1 diabetes, take insulin or a sulfonylurea, are pregnant or breastfeeding, or have any history of disordered eating.

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Criteria: Alberti KGMM, Eckel RH, Grundy SM, et al. Harmonizing the metabolic syndrome. Circulation. 2009;120(16):1640 to 5. PMID 19805654. Source. The waist figures are the set used in the United States. That consensus left waist to national and regional numbers rather than setting one for the world.